Modified fragment of human growth hormone. 30+ peer-reviewed preclinical studies. 99%+ HPLC-verified purity. 3-lab independent COA on every batch.
AOD-9604 (Anti-Obesity Drug 9604) is a modified fragment of human growth hormone corresponding to amino acids 176-191 of the hGH polypeptide. It was specifically engineered to isolate the fat-metabolizing region of growth hormone while excluding the growth-promoting effects associated with full-length hGH.
The fat-specific GH fragment demonstrates lipolytic activity without growth-promoting effects in preclinical models. With 30+ publications, AOD-9604 has been studied in fat metabolism signaling, lipolytic pathway activation, and cartilage repair models.
AOD-9604 is classified as a research-use-only compound. It is not FDA-approved for any therapeutic indication. All references below describe preclinical (in vitro or animal model) research contexts, not human clinical outcomes.
Studied in preclinical models examining adipose tissue lipolysis activation. Research explores beta-3 adrenergic receptor interaction and fat oxidation pathways independent of IGF-1 elevation.
A defining characteristic of AOD-9604 — preclinical studies demonstrate fat-reducing activity without the diabetogenic, growth-promoting, or IGF-1-elevating effects of full-length GH. This separation of effects is a key research focus.
Emerging research examines AOD-9604's role in chondrocyte proliferation and cartilage matrix synthesis models, suggesting potential applications beyond fat metabolism in musculoskeletal research.
Preclinical studies explore AOD-9604's interactions with metabolic signaling cascades including glucose uptake modulation and energy expenditure pathways in adipose tissue models.
Research-grade AOD-9604 with 3-lab COA verification is available at SMART MD Peptides in a 5mg formulation. Every batch is publicly verifiable at smartmdpeptides.com/verify.
99%+ HPLC-verified purity across all AOD-9604 batches. Each batch is independently verified by 3 U.S. laboratories — HPLC for purity, mass spectrometry for molecular weight, and LAL endotoxin assay for safety.
AOD-9604 is the fat-specific GH fragment (amino acids 176-191). In preclinical models, it demonstrates lipolytic activity without the growth-promoting, diabetogenic, or IGF-1-elevating effects associated with full-length growth hormone.
AOD-9604 is legal to acquire for research purposes. It is classified as a research-use-only compound — not FDA-approved for therapeutic use, not intended for human consumption. Licensed researchers and physicians may acquire it for research protocols.
Lyophilized (unreconstituted) AOD-9604 should be stored at -20°C, protected from light. Once reconstituted, store at 2-8°C and use within the timeframe specified on your lot-specific documentation.
Check the COA before you buy. Compare it against any other supplier's documentation.